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[http://en.wikipedia.org/wiki/James_Lancaster Captain James Lancaster] was appointed "General" of the fleet and sailed in the [http://en.wikipedia.org/wiki/Red_Dragon_(1595) 'Red Dragon']. John Middleton was 'Vice-Admiral'. Other ships were the [http://www.eicships.info/ships/shipdetail.asp?sid=111 'Susan'], the [http://www.eicships.info/ships/shipdetail.asp?sid=57 'Hector'], the [http://www.eicships.info/ships/shipdetail.asp?sid=9 'Ascension'] and the [http://www.eicships.info/ships/shipdetail.asp?sid=1483 'Guest']. The fleet captured a Portuguese vessel off the coast of Guinea and took her cargo of wine, oil and meal. After calling at [http://en.wikipedia.org/wiki/Saldanha_Bay Saldanha] at the Cape of Good Hope, Madagascar and Nicobar, they reached [http://en.wikipedia.org/wiki/Aceh Achin] on the northern tip of Sumatra where they were able to secure a cargo of pepper, cinamon and spices. The 'Susan' went to [http://en.wikipedia.org/wiki/Pariaman Priaman] on the coast of Sumatra where she obtained a cargo and sailed for home. Lancaster sent the 'Ascension' back with despatches and proceeded to [http://en.wikipedia.org/wiki/Bantam_(city) Bantam] where he was able to establish a [http://en.wikipedia.org/wiki/Factory_(trading_post) factory]. He the sent a pinnace to trade in the [http://en.wikipedia.org/wiki/Moluccas Moluccas] while he turned for home. An account of the voyage is given in [http://www.archive.org/stream/lettersreceivedb01east#page/n27/mode/2up Letters received by the East India Company Vol I (1602-13)].

The third expedition comprised the 'Dragon' under [http://en.wikipedia.org/wiki/William_Keeling Capt William Keeling], the 'Hector' under Capt William Hawkins and the [http://www.eicships.info/ships/shipdetail.asp?sid=26 'Consent'] under Capt David Middleton. They departed Tilbury on 17 March 1607 and reached [http://en.wikipedia.org/wiki/Saint_Augustin,_Madagascar St Augustine's Bay], Madagascar, via Sierra Leone where the fleet split up. The 'Dragon' took on a cargo and returned reaching England in September 1609. Capt Keeling took a pinnace to [http://en.wikipedia.org/wiki/Banda_Islands Banda] where his attempt to establish a factory was frustrated by the Dutch. He visited Pulau Aye and [http://wikimapia.org/6762008/Pulau-Run Pulau Run] before returning to Bantam via [[Jakarta]] with such spices as he could obtain. He left Bantam with a cargo of pepper and arrived in England on 10 May 1610. The 'Hector' took Capt Hawkins to [[Surat]] where she remained. The 'Consent' went from Bantam to [http://www.britannica.com/EBchecked/topic/86791/Buton Bouton] in the Celebes where he loaded a cargo of spices returning via Bantam to England in early January 1609. An account of the voyage is given in [http://www.archive.org/stream/lettersreceivedb01east#page/n31/mode/2up Letters received by the East India Company Vol I (1602-13)].

For the sixth expedition the Company built two new vessels. [http://www.oxforddnb.com/index/18/101018673/ Sir Henry Middleton] in the [http://www.eicships.info/ships/shipdetail.asp?sid=120 'Trades Increase'] commanded the fleet, Nicholas Downton was captain of the pinnace [http://www.eicships.info/ships/shipdetail.asp?sid=86 'Peppercorn'] and Robert Larkyn captain of the [http://www.eicships.info/ships/shipdetail.asp?sid=28 'Darling']. They left London on 1 April 1610 and arrived in [[Aden]] on 7 November. On proceeding to [http://en.wikipedia.org/wiki/Mocha,_Yemen Mocha] they were made prisoner but escaped and left again on 9 August 1911. They reached [[Surat]] on 26 September but were opposed by the Portuguese and did little trade. The fleet went south to [http://en.wikipedia.org/wiki/Dapoli Dabul] and captured two vessels from [[Cochin]] whose cargoes they removed. From Dabul the fleet went back to Aden which they reached on 1 April 1912. Several vessels were captured in the [http://en.wikipedia.org/wiki/Bab-el-Mandeb Bab el Mandeb] entrance to the Red Sea and they met [http://en.wikipedia.org/wiki/John_Saris Captain John Saris ] of the 8th expedition with the Company ships [http://wwwen.eicshipswikipedia.infoorg/shipswiki/shipdetail.asp?sid=22 Clove_(ship) 'Clove'], [http://www.eicships.info/ships/shipdetail.asp?sid=57 'Hector'] and [http://www.eicships.info/ships/shipdetail.asp?sid=115 'Thomas']. On 19 May 1612 the 'Darling' and the 'Thomas' were despatched to [http://www.fallingrain.com/world/ID/24/Tiku.html Tiku]. The 'Trades Increase' and 'Peppercorn' left Aden on 16 August arriving at Tiku on 19 October. They proceeded to Bantam where the 'Trades Increase' was leaking badly and had to be beached. Shortly after she was destroyed by fire. The 'Peppercorn' left Bantam on 20 December 1612 and reached [http://en.wikipedia.org/wiki/Waterford Waterford] on 13 September 1613 where Captain Downton was arrested for piracy. He was released however and reached London on 19 November. The 'Peppercorn was the only vessel to return. Sir Henry Middleton died at Bantam on 24 May 1613. On 10 March 1614 the 'Darling' left Bantam calling at [http://www.tageo.com/index-e-id-v-11-d-m3742655.htm Succadana] and [http://www.fallingrain.com/world/ID/11/Sambas.html Sambas] on the Borneo coast. She became past repair however and had to be abandoned with her cargo at [http://www.fallingrain.com/world/TH/69/Pattani.html Patani] on the east Malay coast in June 1615. Captain Larkyn took a junk from Succadana to [http://en.wikipedia.org/wiki/Banjarmasin Banjermassin] where he secure a good cargo which he took to Bantam. Despite all the losses a good profit was made on the expedition.